FUNDED PROJECTS:
RESPIRATORY DISEASES
In the 2024 edition, dedicated to respiratory diseases, 94 projects were presented. They were evaluated according to their quality, methodology and relevance by 93 international scientific specialists in this discipline. The evaluation was managed by the Catalan Agency for Health Technology Assessment and Research (AQuAS), which is part of the Catalan Department of Health. Following the proposal of the Scientific Advisory Committee of the Fundació La Marató de TV3, the Board of the Foundation agreed the allocation of €9,076,145 among the 36 research projects listed below:
Transforming pneumonia therapy: miRNA-nanocarriers for immunomodulation and lung repair (Carri-Air)
- Dra. Aina Areny BalagueróInstitut d'Investigació i Innovació Parc Taulí (I3PT)
- Dr. Juan Pellico SáezInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC)
- Dra. Irene Aldás CriadoInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 398.836 €
Evidence-based decisions for pneumonia prevention in Sierra Leone: a study on viral clinical severe pneumonia in African children
- Dra. Azucena Bardají AlonsoInstitut de Salut Global Barcelona (ISGLOBAL)
- Dr. Mohamed SamaiCollege of Medicine and Allied Health Sciences (COMAHS), Universitat de Sierra Leone
Fund: 299.999 €
DUAL-PAH: Synergistic targeting of TGF-β and cGMP-PKG to reverse vascular remodeling in pulmonary arterial hypertension
- Dra. Isabel Blanco VichFundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
- Dr. Víctor Ivo Peinado CabréInstitut d'Investigacions Biomèdiques de Barcelona (IIBB-CSIC)
Fund: 299.999 €
Towards real-time genomic epidemiology for Mycobacterium tuberculosis transmission control in Catalonia (fasTB-SEQ)
- Dr. Pere-Joan Cardona i IglesiasInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 199.266 €
Development of a pathogen- and host-oriented diagnostic test for early detection of invasive pulmonary aspergillosis (ASPIRA)
- Dr. David de Gonzalo CalvoInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Fund: 199.413 €
Randomized, double-blind, parallel-group clinical trial, compared with placebo to evaluate the efficacy and safety of three antibiotic treatment regimens for the eradication of P. aeruginosa in patients with bronchiectasis
- Dr. David de la Rosa CarrilloInstitut de Recerca Hospital de la Santa Creu i Sant Pau (IR-Sant Pau)
Fund: 200.000 €
Impact of vaping (e-cigarettes) on the (epi)genome of adult users
- Dr. Manel Esteller BadosaInstitut de Recerca contra la Leucèmia Josep Carreras
Fund: 200.000 €
Combined effectiveness of antibiotics and bacteriophages for personalised treatment of ventilator-associated pneumonia caused by Pseudomonas aeruginosa
- Dra. Laia Fernández BaratFundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Fund: 199.993 €
Smoke-Free Homes intervention to improve children’s respiratory health: an effectiveness and implementation study in primary care paediatric services
- Dra. Marcela Fu BalboaInstitut Català d'Oncologia-Institut d'Investigació Biomèdica de Bellvitge (ICO-IDIBELL)
- Dr. Pere Toran MontserratInstitut per a la Recerca i l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAP Jordi Gol)
Fund: 299.982 €
Stick your tongue out at tuberculosis: Evaluation of tongue swabs for TB diagnosis among household contacts
- Dr. Alberto García-BasteiroInstitut de Salut Global Barcelona (ISGLOBAL)
- Dr. Sozinho AcácioCentro de Investigaçao em Saúde de Manhiça (CISM), Moçambic
- Dr. Antoni Noguera JuliánFundació Sant Joan de Déu per a la Recerca
Fund: 399.775 €
Spatial transcriptomics and AI-driven analysis in chronic allograft dysfunction
- Dra. Susana Gómez OllésVall d'Hebron Institut de Recerca (VHIR)
- Dra. Eva María Revilla LópezHospital Universitari Vall d’Hebron
- Dr. Bart VanaudenaerdeUniversitat Catòlica de Lovaina (Katholieke Universiteit Leuven), Bèlgica
- Dra. Paula Petrone ForbesBarcelona Supercomputing Center (BSC)
Fund: 399.981 €
Cost-effectiveness and cost of implementation of a lung cancer screening program
- Dra. Jèssica González GutiérrezInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Fund: 138.457 €
Advancing microbiological approach for the treatment of chronic pulmonary infections caused by Mycobacterium avium complex and mycobacteroides abscessus complex
- Dr. Julià González MartínInstitut de Salut Global Barcelona (ISGLOBAL)
Fund: 196.005 €
Impact of hematopoiesis in lung fibrosis and tissue regeneration
- Dra. Raquel Guillamat PratsInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 184.375 €
Novel host-directed broad-spectrum anti-influenza A antivirals to cross protect humans and key susceptible reservoir species
- Dra. Nuria Izquierdo-UserosFundació Privada Institut de Recerca sobre immunopatologies Caixa IrsiCaixa
- Dra. Júlia Vergara AlertInstitut de Recerca i Tecnologia Agroalimentàries-Centre de Recerca en Sanitat Animal (IRTA-CReSA)
Fund: 265.125 €
Translating candidate causal genes in human respiratory disease using Drosophila melanogaster
- Dra. Sofía Jorge de Moura Míguez AraujoUniversitat de Barcelona (UB)
- Dr. Marios GeorgiouSchool of Life Sciences, Universitat de Nottingham, United Kingdom
- Dr. Ian SayersSchool of Medicine, Universitat de Nottingham, United Kingdom
Fund: 399.999 €
Targeting diaphragmatic fatigue in ALS: Myokine-based strategies for neuromuscular preservation
- Dra. María Ángel Lanuza EscolanoUniversitat Rovira i Virgili-Institut d'Investigació Sanitària Pere Virgili (IISPV)
Fund: 198.336 €
New insights into immunity and host-pathogen interactions across the tuberculosis spectrum – TB-SPECTRUM
- Dra. Irene Latorre RuedaInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 199.971 €
Towards a broadly applicable class of anti-influenza virus agents acting as dual binding site inhibitors of the viral hemagglutinin
- Dr. Francisco Javier Luque GarrigaUniversitat de Barcelona (UB)
- Dra. Lieve NaesensUniversitat Catòlica de Lovaina (Katholieke Universiteit Leuven), Belgium
Fund: 299.875 €
Anticipation of respiratory outcomes in patients with acute hypoxemic respiratory failure (AHRF) treated with high-flow nasal cannula using omics and clinical data (CNAFOMICS)
- Dr. Joan Ramon Masclans EnvizInstitut Hospital del Mar d'Investigacions Mèdiques (IMIM)
- Dr. Santiago Marco ColásInstitut de Bioenginyeria de Catalunya (IBEC)
Fund: 299.274 €
Enhancing respiratory infection care: Effectiveness of structured clinical pathways in lowering hospitalization and mortality. (ERIC study: Enhancing Respiratory Infection Care)
- Dra. Esperanza Merino de LucasInstitut d'Investigació Sanitària I Biomèdica d'Alacant (ISABIAL)
Fund: 199.574 €
Epigenetic profiles and environmental exposome in radon-associated lung cancer: The REXPIRE Study
- Dra. Laura Mezquita PérezFundació Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Fund: 189.544 €
Is there a relationship between respiratory syncytial virus lower respiratory tract infection and preschool recurrent wheezing? An observational cohort study after universal nirsevimab prophylaxis implementation
- Dr. Antonio José Moreno GaldóVall d'Hebron Institut de Recerca (VHIR)
- Dr. José María Martínez SánchezUniversitat d'Extremadura
- Dra. Laura Soler ColomerInstitut per a la Recerca i l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAP Jordi Gol)
Fund: 333.750 €
Involvement of IGFBP3 in the regulation of lung stem cells in the tumourigenic process in NSCLC
- Dr. Alfons Navarro PonzFundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Fund: 151.250 €
Legionnaires' disease in Catalonia: Intervention study on diagnostic methodology
- Dra. Noemí Párraga NiñoInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 139.158 €
Exploring the dynamic interplay between pulmonary fibrosis and lung cancer pathways (FIBROCAN): Unveiling a complex dance
- Dra. Karina Portillo CarrozInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IIGTP)
Fund: 188.125 €
Development of a nasal spray for prophylaxis against respiratory viruses (RSV and IAV) (RESProtect)
- Dra. Dàlia Raïch ReguéInstitut de Recerca sobre Immunopatologies-Caixa IrsiCaixa
Fund: 200.000 €
Discovery, synthesis, and preclinical validation of a novel airway smooth muscle anti-remodeling therapeutic from mesenchymal stem cell secretome-derived proteins for asthma
- Dr. David Ramos BarbónInstitut de Recerca Hospital de la Santa Creu i Sant Pau (IR-Sant Pau)
Fund: 199.936 €
Protecting respiratory health in Catalonia: Climate, pollution, and patient perspectives (PRISMA-CAT)
- Dr. Otavio RanzaniInstitut de Salut Global Barcelona (ISGLOBAL)
- Dra. Talita Duarte-SallesInstitut per a la Recerca i l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAP Jordi Gol)
Fund: 299.999 €
Synthetic virus-like protein assemblies in cell-free systems for precision antimicrobial therapy against respiratory pathogens (ASSEMBLY)
- Dr. Guillermo Rodrigo TárregaInstitut de Biologia Integrativa de Sistemes (i2sysbio-CSIC), València
Fund: 199.625 €
Exercise-induced laryngeal obstruction (EILO) in children and adolescents with exercise-induced dyspnea: From prevalence and characterization to improving diagnosis through AI-powered acoustic respiratory analysis
- Dr. Diego Agustín Rodríguez ChiarabiaInstitut Hospital del Mar d'Investigacions Mèdiques (IMIM)
- Dr. Manuel Lozano GarcíaInstitut de Bioenginyeria de Catalunya (IBEC)
Fund: 300.000 €
Inhibiting respiratory virus fusion with anti-amyloid compounds: From proof-of-concept to pandemic preparedness
- Dr. Raimon Sabaté LagunasUniversitat de Barcelona (UB)
Fund: 200.000 €
Revolutionizing early sleep apnea diagnosis: new mHealth solutions for accessible sleep monitoring in adult and children populations with different health conditions (mScreenSleep)
- Dra. Júlia Sampol SirventVall d'Hebron Institut de Recerca (VHIR)
- Dra. Yolanda Castillo EscarioInstitut de Bioenginyeria de Catalunya (IBEC)
Fund: 299.750 €
Early identification of treatment failure in pulmonary sarcoidosis through integrated multi-omic analysis: The PREDICT-SARC study
- Dr. Jacobo Sellarés TorresFundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
- Dr. Iván Castellví BarrancoInstitut de Recerca Hospital de la Santa Creu i Sant Pau (IR-Sant Pau)
- Dra. Ana Villar GómezVall d'Hebron Institut de Recerca (VHIR)
- Dra. Vanesa Vicens ZygmuntInstitut d'Investigació Biomèdica de Bellvitge (IDIBELL)
Fund: 399.338 €
Identification of key molecules with antifibrotic effects from the secretome of alveolar type II cells for the development of new therapies for idiopathic pulmonary fibrosis
- Dra. Anna Serrano MollarInstitut d'Investigacions Biomèdiques de Barcelona (IIBB-CSIC)
- Dr. Pedro Melgar-LesmesUniversitat de Barcelona (UB)
Fund: 299.851 €
TheRapeutic StrAtegies for obstructive sleeP apnea in older adults with overweigHt or obesity: A randomizEd clinical triaL (RAPHAEL study)
- Dr. Adriano Targa Dias SantosInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Fund: 197.584 €